Don’t dismiss the threat of meningococcal disease
Time After Onset of Symptoms2,*
Hypothetical case in an individual 15-16 years old.
*Hours expressed as medians.
†Seizure was noted at a median of 26 hours.
Data were obtained from parents of test subjects via questionnaire (n=313) or interview with a study investigator (n=135). Parents were asked at what time of day their child’s symptoms began, as well as the time of appearance of predefined clinical features. Additional data were obtained from medical records for the course of illness before admission to the hospital in 448 children (≤16 years of age) with meningococcal disease (345 nonfatal cases; 103 fatal). Diagnosis was confirmed with microbiologic techniques in 83% of cases (n=373). The remainder of the children (n=75) were probable cases.2
Did you know outbreaks can happen on college campuses?
Vaccination may not protect all recipients.
References: 1. Pelton SI. Meningococcal disease awareness: clinical and epidemiological factors affecting prevention and management in adolescents. J Adolesc Health. 2010;46:S9-S15. 2. Thompson MJ, Ninis N, Perera R, et al. Clinical recognition of meningococcal disease in children and adolescents. Lancet. 2006;367(9508):397-403. 3. Meningococcal disease. In: Hamborsky J, Kroger A, Wolfe S, eds. Epidemiology and Prevention of Vaccine-Preventable Diseases. 13th ed. Washington, DC: Public Health Foundation; 2015;231-245. http://www.cdc.gov/vaccines/pubs/pinkbook/mening.html. Reviewed April 15, 2019. Accessed January 16, 2020. 4. McNamara LA, Blain A. Meningococcal Disease. In: Roush SW, Baldy LM, Hall MAK, eds. Manual for the Surveillance of Vaccine-Preventable Diseases. National Center for Immunization and Respiratory Diseases. https://www.cdc.gov/vaccines/pubs/surv-manual/chpt08-mening.html. Updated December 27, 2019. Accessed March 12, 2020. 5. Centers for Disease Control and Prevention. Meningococcal disease: Technical and clinical information. http://www.cdc.gov/meningococcal/clinical-info.html. Updated May 31, 2019. Accessed January 16, 2020. 6. Slack R, Hawkins KC, Gilhooley L, Addison GM, Lewis MA, Webb NJ. Long-term outcome of meningococcal sepsis-associated acute renal failure. Pediatr Crit Care Med. 2005;6(4):477-479. 7. Vyse A, Anonychuk A, Jäkel A, et al. The burden and impact of severe and long-term sequelae of meningococcal disease. Expert Rev Anti Infect Ther. 2013;11(6):597-604. 8. Centers for Disease Control and Prevention. Meningococcal disease: Causes and transmission. http://www.cdc.gov/meningococcal/about/causes-transmission.html. Updated May 31, 2019. Accessed January 16, 2020.
Trademarks are owned by or licensed to the GSK group of companies.
This website is funded and developed by GSK.
This site is intended for US healthcare professionals only.
The GSK Response Center is available to answer your questions at 1-888-593-5977, Monday-Friday, 8:30 am - 5:30 pm ET.
During the hours the GSK Response Center is not available, please feel free to Contact GSK.